The best toothpaste should contain fluoride to fight cavities — other ingredients depend on your teeth. After speaking with dentists about common oral hygiene issues, digging into existing research, and brushing our teeth til they glowed, we found top picks in four categories: general purpose, whitening, sensitive, and natural toothpaste.

Best General Use Toothpaste

A multi-purpose toothpaste good for those with no specific dental issues. Clinically proven to prevent and reduce cavities, gingivitis, plaque, and bad breath, and sensitivity.

Best Toothpaste for Sensitive Teeth

Sensodyne ProNamel Fresh Breath Toothpaste
The least abrasive of all the toothpastes we tested, with 5 percent potassium nitrate to reduce pain while brushing.

Best Whitening Toothpaste

A formula that’s gritty enough to reduce surface-level stains on teeth, but gentle enough for everyday use.

Best Natural Toothpaste

The Natural Dentist Healthy Teeth & Gums Anti-Cavity Toothpaste in Peppermint Twist
This fluoride toothpaste is free of sodium lauryl sulfate, artificial dyes, and artificial sweeteners.

The Best Toothpastes

Our top pick for a daily general-use toothpaste is Crest Pro-Health Original Flavor Toothpaste in Clean Mint. Crest Pro-Health is the only line of toothpaste we found that uses stannous fluoride, rather than the more common sodium fluoride. In addition to stopping cavities, stannous fluoride doubles as an antibacterial agent, allowing Crest Pro-Health to target plaque, gingivitis, and bad breath on top of tooth decay. The product also whitens your teeth, prevents sensitivity, and has verification from the ADA to back up all of its claims. It was the most genuinely multi-purpose toothpaste we could find.

Wondering whether you really need all that? If so, we’d suggest checking out our two general use runners-up, Benco Dental PRO-SYS Mint Flavored Fluoride Toothgel and Colgate Cavity Protection. Both rely on sodium fluoride to offer cavity protection and nothing else — and some of our dental experts suggest this is all you really need. Colgate has a very mild mint flavor and lots of froth, while Benco PRO-SYS is a pleasant, spearmint-flavored gel.

Our pick for sensitive teeth is Sensodyne ProNamel Fresh Breath Toothpaste. It was the least abrasive of all the toothpastes we tested — gentle enough for teeth with thin layers of enamel — and contains 5 percent potassium nitrate to numb your mouth. It does have a strong peppermint flavor, so some of our testers preferred Colgate Sensitive Prevent & Repair Toothpaste, a runner-up that’s slightly more abrasive but less minty.

Whitening toothpastes have limited powers: they can remove surface-level stains but won’t help much if you’re worried about general yellowing. With that caveat in mind,Tom’s of Maine Simply White Natural Fluoride Toothpaste in Sweet Mint stood out as our favorite, with a high level of abrasiveness to remove surface stains, but a surprisingly smooth, non-gritty texture. Unlike many “whitening” toothpastes, its claims have also been vetted by the ADA. It edged out runner-up Crest Pro-Health Extra Whitening Power Toothpaste by a hair: Crest works similarly, but was more polarizing among testers thanks to an extremely gritty texture.

For a natural pick, we’d suggest The Natural Dentist Healthy Teeth & Gums Anti-Cavity Toothpaste in Peppermint Twist. It does contain fluoride, per the advice of every dental expert we consulted, but it’s free of sodium lauryl sulfate, which can cause canker sores, as well as artificial dyes and sweeteners.

Our Picks for the Best Toothpaste

Best General Use Toothpaste

Crest Pro-Health Original Flavor Toothpaste Clean MintFights cavities, gingivitis, bad breath, plaque and sensitivity while removing surface stains.

We were initially skeptical of Crest Pro-Health’s claim to prevent tooth decay, gingivitis, plaque, bad breath and sensitivity — all while whitening your teeth. But this product received the ADA Seal of Acceptance in all six areas, which means it’s got research to back it up. And after digging into that research, we were impressed.

Crest Pro-Health’s efficacy is partly explained by the product’s use of stannous fluoride rather than sodium fluoride. Both types protect equally against cavities, but stannous also has antibacterial properties, which allows Crest Pro-Health to fight gingivitis and plaque — which are caused by bacteria building up in your mouth. Crest Pro-Health was the only toothpaste we tested that used stannous fluoride.

Crest-Close-Up for Best Toothpaste

So why don’t more companies jump on the bandwagon? In theory, stannous fluoride doesn’t taste as good as sodium fluoride. Sodium fluoride is also cheaper to produce. And stannous earned a bad reputation when it was first introduced due to the fact that it caused temporary staining (think white blotches) on the teeth of a handful of users. But newer formulations seem to eliminate this drawback. “Stannous got a bad rap in the early 2000s for its staining,” says Turchetta. “Today it’s a force to reckon with for those who are taking control of their oral health.”

What changed? When the Pro-Health line was introduced in 2005, Crest introduced a new stabilized stannous fluoride and added a whitening agent called sodium hexametaphosphate. Combined, these two ingredients result in a toothpaste with the extra antibacterial benefits of stannous fluoride, but without the risk of staining.

“I’ve recently discovered a new love for stannous fluoride. Recent tech has gifted us with the ability to have stannous benefits without staining. Stannous has antibacterial properties, it helps rebuild enamel, and it also helps with sensitivity.”

Anastasia TurchettaRegistered Dental Hygienist

We also couldn’t detect any taste difference between Crest Pro-Health and products containing sodium fluoride. In fact, we found Arm & Hammer Dental Care Advance Cleaning Daily Fluoride Toothpaste with Baking Soda more bitter than Crest Pro-Health. We ran our tests with Crest’s Clean Mint formulation, a spearmint that was middle-of-the-road: not too strong, not too mild. “Great flavor,” one tester reported.

We were less enthusiastic about the slight grittiness of Crest Pro-Health. Crest’s website calls the particles in their toothpaste “ActivClean crystals,” but you’ll see them on the ingredient list under “sodium hexametaphosphate.” These serve as an anti-staining and tartar prevention ingredient, but if you prefer a smoother brushing experience, you might want to check out one of our runners-up. The gel itself is also quite soft and tended to drip when we opened the cap. But if you want a toothpaste that does it all, Crest Pro-Health is the most comprehensive option. One 5-ounce tube is about $5.

No-Frills Runners-up

Benco Dental PRO-SYS Mint Flavored Fluoride ToothgelSpearmint-flavored cavity protection in a stand-up tube.

If you’re looking for a general use toothpaste that protects against cavities — and nothing else — we were impressed by Benco Dental PRO-SYS Mint Flavored Fluoride Toothgel. It’s a nice spearmint-y gel that left no bitterness or aftertaste during testing and is less gritty than Crest Pro-Health. We also appreciated the tube design: PRO-SYS stands upright, which means it won’t require rolling as it empties. At a little over $1 for 4 ounces, it was one of the cheapest options that we tested. And with sodium fluoride as an active ingredient, it will do exactly what it claims: prevent and reduce tooth decay.

Colgate Cavity Protection ToothpasteCavity protection with a very mild flavor and lots of froth.

Colgate Cavity Protection Toothpaste is another excellent no-frills option, especially if you don’t like strong flavor. It’s a mild spearmint paste — so mild that its flavor faded before our testers finished brushing — and it’s also notably foamier than both Benco PRO-SYS and Crest Pro-Health. This toothpaste relies on fluoride in the form of sodium monofluorophosphate to protect against tooth decay, and while it’s a few cents more expensive than PRO-SYS, it’s also a more recognizable name brand and may be easier to spot on the grocery store shelf.

Best for Sensitive Teeth

Sensodyne ProNamel Fresh Breath ToothpasteFluoride plus potassium nitrate to stop cavities and alleviate sensitivity.

If you have sensitive teeth and gums and aren’t afraid of bold flavor, we highly recommend Sensodyne’s ProNamel Fresh Breath toothpaste.

Like most sensitivity toothpastes, it contains five percent potassium nitrate, a chemical compound that protects and desensitizes nerve fibers in the mouth. If you experience discomfort while brushing, or when eating hot or cold foods, ProNamel will bring temporary relief. It also has a strong peppermint flavor that left our mouths feeling fresh.

Pro-Namel-Close-Up for Best Toothpaste

Sensitive toothpastes are typically less abrasive than other toothpastes, which makes sense: using a lot of grit on sensitive teeth is like rubbing sand into an open wound. Ouch. And there’s actually a technical way to measure a toothpaste’s grittiness: Relative Dentin Abrasivity, or RDA. The ADA says that anything with an RDA of less than 250 won’t damage your teeth. But for sensitive teeth, most dental experts recommend an RDA under 100. ProNamel’s RDA is 34, one of the lowest we found.

How abrasive is your toothpaste?You can Google “RDA toothpaste” and find a number of charts that list the RDAs for common toothpaste brands. Crest Pro Health, our top pick, has an RDA of 150.

As an added precaution, Sensodyne ProNamel is also free of sodium lauryl sulfate (SLS). For most people, SLS merely serves to create foam as you brush, but it can sometimes cause canker sores. Skipping the SLS ensures that Sensodyne ProNamel is as gentle as possible on your mouth. The tradeoff is that it’s also less frothy than standard options like Colgate Cavity Protection. Testers still noted bubbles as they brushed — just not as many.

ProNamel is a little pricier than many of our contenders, with a 4-ounce tube retailing for about five dollars. Colgate Prevent & Repair, by comparison, comes in a 6-ounce tube for $4.

Sensitivity Runner-up:

Colgate Sensitive Prevent & Repair ToothpasteSlightly more abrasive, but a milder flavor.

Some of our testers found Sensodyne’s minty flavor too strong, to the point that it stung their mouths. If you prefer a milder flavor, we’d suggest giving Colgate Sensitive Prevent & Repair toothpaste a try. Like Sensodyne, it contains five percent potassium nitrate. Its RDA rating is 63, which means it’s slightly more abrasive, but this difference wasn’t noticeable when we brushed with it. Even our testers with sensitive teeth reported no pain.

We also considered Tom’s of Maine Natural Maximum Strength Sensitive, but it carried a warning that it shouldn’t be used for longer than four weeks without a doctor’s recommendation — unlike Sensodyne, which is expressly marketed as a “daily fluoride toothpaste.” Tom’s of Maine does have the same active ingredients as Sensodyne, so the warning might be just a precaution. If you’re looking for a Sensodyne alternative, it’s worth running past your dentist.

Best Whitening Toothpaste

Tom’s of Maine Simply White Natural Fluoride Toothpaste Sweet MintADA-certified to remove surface stains via gentle abrasion.

The truth is, toothpaste really can’t whiten teeth; that takes a dedicated teeth whitening product containing hydrogen or carbamide peroxide, which gets past enamel and works on your teeth’s underlying dentin. Some whitening toothpastes do contain a small amount of peroxide, but it stays in your mouth for such a short period of time that its benefits are negligible. What a whitening toothpaste can do is remove surface stains from food like coffee and red wine by upping its percentage of abrasives.

For this category, we liked Tom’s of Maine Simply White Natural Fluoride toothpaste. It doesn’t have any harsh bleaching chemicals, instead using hydrated silica to give teeth a gentle scrubbing. It has also earned the ADA Seal of Acceptance, indicating that it is effective at both preventing tooth decay and making teeth appear whiter.

Toms-Close-Up for Best Toothpaste

Hydrated silica is the first ingredient on the list after fluoride, unlike runner-up Crest Pro-Health Extra Whitening Power, which features hydrated silica slightly lower down. We were pleasantly surprised by the consistency of Tom’s, which was smooth and free of grit. Testers did note a very faint bitterness but said “it wasn’t bad,” and they liked the mild froth produced by brushing.

Tom’s also boasts a refreshingly short ingredient list, lacking both artificial dyes and flavors (though it does contain SLS). We were a little confused by the packaging, which features a vanilla flower despite no discernible vanilla in the product. But we liked the very mild, minty flavor, though it dissipated quickly. $4 for 4.7 ounces.

Whitening Runner-up:

Crest Pro-Health Whitening Power ToothpasteAlso ADA-certified, with a grittier texture.

We also tested and liked Crest Pro-Health Extra Whitening Power. It is notably grittier than Tom’s of Maine, with one tester reporting, “you could sort of chew it and feel the grit.” Some of our testers liked this, and some didn’t, but the product definitely left our teeth feeling scrubbed. $3 for 7 ounces.

Best Natural Toothpaste

The Natural Dentist Healthy Teeth & Gums Anti-Cavity Toothpaste Peppermint TwistNo sodium lauryl sulfate, artificial dyes, or artificial sweeteners. Contains fluoride.

The term “natural” isn’t regulated by the FDA, which means it’s often used as a marketing gimmick (a lesson we learned when we tested natural deodorants). So for natural toothpaste, we developed our own criteria: it still had to have fluoride, but we wanted a product free of sodium lauryl sulfate (SLS) and artificial dyes, with as few artificial flavors and sweeteners as possible.

The Natural Dentist was a winner on all fronts. The only coloring agent it contains is titanium dioxide, a naturally occurring pigment used to give the paste its white color (a pleasant change from the “blue 1” and “red 30” of brands like Aquafresh). It’s also free of artificial sweeteners, flavored instead with a combination of sorbitol and xylitol — naturally occurring sugar alcohols — plus natural flavor.

Natural-Dentist--Toothpaste to go after the second paragraph of each minireview

Testers did find the flavor unusual. It’s described as “Peppermint Twist,” but we were met with a strong burst of anise when we began to brush and could barely detect any peppermint at all. The flavor also faded quickly, though our mouths ultimately felt fresh, with one tester noting that her “tongue felt cleaner” than with any of the other toothpaste she’d tested. The Natural Dentist had no discernible aftertaste, unlike runner-up Biotene, which had a faint bitter flavor that lingered.

Though it doesn’t carry the ADA Seal of Acceptance, The Natural Dentist does contain fluoride (sodium fluoride, in this case), so you’ll be getting the full benefits of cavity protection. It also contains a number of natural ingredients like aloe leaf juice and echinacea extract, which have anti-inflammatory properties. We couldn’t find any research about the benefits of these ingredients in toothpaste specifically, but they certainly don’t hurt. A 5-ounce tube retails for about $5.

If you want to explore your options, Biotene Fluoride Toothpaste Fresh Mint Original and CloSYS Sulfate-Free Fluoride Toothpaste Mild Mint are also worth considering. Neither contains extras like aloe or echinacea, but both avoid SLS and artificial dyes. They do contain “flavor” on the ingredient list, along with sucralose, an artificial sweetener, and they’re slightly more expensive: Biotene is $8 for a 4.3-ounce tube, and CloSYS is $11 for 7 ounces.

Did You Know?

Some foods might be good for your teeth.

Everyone knows that to keep your teeth in good shape, you should avoid candy. But some foods might actively help your teeth. According to the University of Rochester Medical Center, dairy products like cheese and milk stimulate saliva. Saliva is your body’s own cavity fighter, attacking the acids and enzymes that damage your teeth. As an added bonus, the calcium and phosphates in dairy products help replace minerals in your teeth that the enzymes have been eating. So from a dental point of view, at least, extra cheese on those nachos is a good thing.

Here’s how to decode your toothpaste ingredient list.

Beyond fluoride, the ingredient list on your average tube may look like gobbledegook, but there are really only a few common ingredient categories. Knowing what they are can make shopping for toothpaste a little less intimidating:

  • Abrasives: These are tiny particles that help scrub away food and plaque. They include substances like hydrated silica, alumina, and mica and generally make up about 50 percent of a toothpaste.
  • Humectants: These substances retain water and keep toothpaste from hardening. Examples include aloe barbadensis gel, pentylene glycol, and PEG-8 (polyethylene glycol).
  • Surfactants: Surfactants are the detergent-like substances that make your toothpaste pleasantly frothy. You’ll find them listed in the ingredients under names like cocamidopropyl betaine, sodium lauryl sarcosinate, and sodium lauryl sulfate.
  • Thickeners and stabilizers: Ingredients like carrageenan, disodium phosphate, and xanthan gum help promote proper consistency of your favorite paste or gel.

Make sure to brush correctly.

Most people rush through their brushing routine. Two minutes, the amount of time the ADA recommends you should spend, seems like an awfully long time when you’re also squinting in the bathroom mirror wondering how to get rid of advanced bed head. The ADA offers these tips for effective brushing:

  • Two minutes, twice a day.
  • Unless your dentist tells you otherwise, use a soft-bristled brush.
  • Use a back-and-forth rather than an up-and-down motion on exterior surfaces.
  • To tackle inside surfaces, hold your brush vertically and use short up-and-down sweeps.
  • Brush your tongue to remove bacteria.
  • Replace your toothbrush every 3-4 months.

The Best Toothpaste: Summed-Up

Take Action

Although toothpaste manufacturers may tweak their recipes to provide added functions such as whitening or pain reduction, it all comes back to one basic ingredient: fluoride. If you choose a toothpaste with fluoride, and use it regularly and as directed, you’ll be doing the single most important thing to maintain excellent oral health.

Don’t forget that regular dentist visits are also important — even more so if you’re dealing with persistent pain or bad breath that toothpaste just doesn’t seem to help. Dr. Hewlett, of the UCLA School of Dentistry, reminded us, “We tell people to talk to your dentist, who is a licensed expert, and with whom you have a relationship. You should trust your dentist.”

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